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BDBM124837 US8759386, 34

SMILES: CCc1c(oc2c(F)cccc12)C(=O)Nc1ccc(Cn2nc(C)c(CC(O)=O)c2C)cc1

InChI Key: InChIKey=QXSIEYYKCAVRMN-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124837   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM124837
PNG
(US8759386, 34)
Show SMILES CCc1c(oc2c(F)cccc12)C(=O)Nc1ccc(Cn2nc(C)c(CC(O)=O)c2C)cc1
Show InChI InChI=1S/C25H24FN3O4/c1-4-18-19-6-5-7-21(26)23(19)33-24(18)25(32)27-17-10-8-16(9-11-17)13-29-15(3)20(12-22(30)31)14(2)28-29/h5-11H,4,12-13H2,1-3H3,(H,27,32)(H,30,31)
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Similars

US Patent
0.300n/an/an/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...


Citation and Details
More data for this
Ligand-Target Pair