BDBM124837 US8759386, 34

SMILES: CCc1c(oc2c(F)cccc12)C(=O)Nc1ccc(Cn2nc(C)c(CC(O)=O)c2C)cc1

InChI Key: InChIKey=QXSIEYYKCAVRMN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124837   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM124837 (US8759386, 34) Show SMILES CCc1c(oc2c(F)cccc12)C(=O)Nc1ccc(Cn2nc(C)c(CC(O)=O)c2C)cc1 Show InChI InChI=1S/C25H24FN3O4/c1-4-18-19-6-5-7-21(26)23(19)33-24(18)25(32)27-17-10-8-16(9-11-17)13-29-15(3)20(12-22(30)31)14(2)28-29/h5-11H,4,12-13H2,1-3H3,(H,27,32)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	-13.0	n/a	n/a	n/a	n/a	n/a	7.4	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8759386 (2014) BindingDB Entry DOI: 10.7270/Q2S46QM5
					More data for this Ligand-Target Pair