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BDBM124847 US8759386, 44

SMILES: Cc1nn(Cc2ccc(NC(=O)c3oc4ccc(Cl)cc4c3C)cc2F)c(C)c1CC(O)=O

InChI Key: InChIKey=RQKLMCHFMQMJNP-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124847   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM124847
PNG
(US8759386, 44)
Show SMILES Cc1nn(Cc2ccc(NC(=O)c3oc4ccc(Cl)cc4c3C)cc2F)c(C)c1CC(O)=O
Show InChI InChI=1S/C24H21ClFN3O4/c1-12-18-8-16(25)5-7-21(18)33-23(12)24(32)27-17-6-4-15(20(26)9-17)11-29-14(3)19(10-22(30)31)13(2)28-29/h4-9H,10-11H2,1-3H3,(H,27,32)(H,30,31)
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Similars

US Patent
0.300n/an/an/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...


Citation and Details
More data for this
Ligand-Target Pair