BDBM124858 US8759386, 55

SMILES: CCCCn1c(cc2cc(F)ccc12)C(=O)Nc1ccc(Cn2nc(C)c(CC(O)=O)c2C)c(F)c1

InChI Key: InChIKey=UEVJRWCAIJJEEZ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124858   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM124858 (US8759386, 55) Show SMILES CCCCn1c(cc2cc(F)ccc12)C(=O)Nc1ccc(Cn2nc(C)c(CC(O)=O)c2C)c(F)c1 Show InChI InChI=1S/C27H28F2N4O3/c1-4-5-10-32-24-9-7-20(28)11-19(24)12-25(32)27(36)30-21-8-6-18(23(29)13-21)15-33-17(3)22(14-26(34)35)16(2)31-33/h6-9,11-13H,4-5,10,14-15H2,1-3H3,(H,30,36)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.100	-13.6	n/a	n/a	n/a	n/a	n/a	7.4	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8759386 (2014) BindingDB Entry DOI: 10.7270/Q2S46QM5
					More data for this Ligand-Target Pair