BDBM124863 US8759365, 5-3

SMILES: CC[C@@H]1C[C@@H](CN1C(=O)C1CCCCC1)N(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1ncc(cn1)-c1cnn(C)c1

InChI Key: InChIKey=OMEMBEXNWIPJBE-FTJBHMTQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124863   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM124863 (US8759365, 5-3) Show SMILES CC[C@@H]1C[C@@H](CN1C(=O)C1CCCCC1)N(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1ncc(cn1)-c1cnn(C)c1 |r| Show InChI InChI=1S/C30H34F6N6O/c1-3-25-12-26(18-41(25)27(43)20-7-5-4-6-8-20)42(28-37-13-21(14-38-28)22-15-39-40(2)17-22)16-19-9-23(29(31,32)33)11-24(10-19)30(34,35)36/h9-11,13-15,17,20,25-26H,3-8,12,16,18H2,1-2H3/t25-,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	92	n/a	n/a	n/a	n/a	7.4	37
Novartis AG US Patent					Assay Description CETP Activity Kit (#RB-RPAK) was purchased from Roar Biochemical, Inc. (New York, N.Y., USA). To each well of a 96-well NBS half-area plate (costar #...				US Patent US8759365 (2014) BindingDB Entry DOI: 10.7270/Q2NG4P95
					More data for this Ligand-Target Pair