BDBM125053 US8772511, 22
SMILES: COc1ccc(NC(=O)Nc2ccc3cc(oc3c2)C(=O)N[C@H]2CN3CCC2CC3)cc1
InChI Key: InChIKey=DTWUJBKFCQXSLJ-FQEVSTJZSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neuronal acetylcholine receptor (Rattus norvegicus (Rat)) | BDBM125053 (US8772511, 22) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | <1 | <-11.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Bayer Intellectual Property GmbH US Patent | Assay Description Rat brain tissue (hippocampus or whole brain) is homogenized in aqueous homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethy... | US Patent US8772511 (2014) BindingDB Entry DOI: 10.7270/Q2GQ6WF2 | |||||||||||
More data for this Ligand-Target Pair |