BDBM125550 US8772316, 33

SMILES: CNc1nc2ccc(C)cc2cc1Cc1c2cc(OC)c(OC)cc2c(C)[nH]c1=O

InChI Key: InChIKey=SVBAVLKSWAONTO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125550   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM125550 (US8772316, 33) Show SMILES CNc1nc2ccc(C)cc2cc1Cc1c2cc(OC)c(OC)cc2c(C)[nH]c1=O Show InChI InChI=1S/C24H25N3O3/c1-13-6-7-20-15(8-13)9-16(23(25-3)27-20)10-19-18-12-22(30-5)21(29-4)11-17(18)14(2)26-24(19)28/h6-9,11-12H,10H2,1-5H3,(H,25,27)(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.4	n/a
Allergan, Inc.; Exonhit Therapeutics SA US Patent					Assay Description The PDE assay is based on the homogenous time-resolved fluorescence resonance energy transfer (TR-FRET) technology (LANCE from Perkin Elmer). This co...				US Patent US8772316 (2014) BindingDB Entry DOI: 10.7270/Q2Q81BR8
					More data for this Ligand-Target Pair