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SMILES: CNc1nc2ccc(OC)cc2cc1Cc1c2cc(OC)c(OC)cc2c(C)[nH]c1=O

InChI Key: InChIKey=FWQGMVUNVROMOR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125554   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))		BDBM125554
PNG
(US8772316, 37)
Show SMILES CNc1nc2ccc(OC)cc2cc1Cc1c2cc(OC)c(OC)cc2c(C)[nH]c1=O
Show InChI InChI=1S/C24H25N3O4/c1-13-17-11-21(30-4)22(31-5)12-18(17)19(24(28)26-13)10-15-8-14-9-16(29-3)6-7-20(14)27-23(15)25-2/h6-9,11-12H,10H2,1-5H3,(H,25,27)(H,26,28)
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Similars
US Patent
n/an/a 6n/an/an/an/a7.4n/a



Allergan, Inc.; Exonhit Therapeutics SA

US Patent


Assay Description
The PDE assay is based on the homogenous time-resolved fluorescence resonance energy transfer (TR-FRET) technology (LANCE from Perkin Elmer). This co...

US Patent US8772316 (2014)


BindingDB Entry DOI: 10.7270/Q2Q81BR8
More data for this
Ligand-Target Pair