BDBM125577 US8772316, 60

SMILES: CNc1nc2cc3OCOc3cc2cc1Cc1c2cc(OC)c(OC)cc2c(C)[nH]c1=O

InChI Key: InChIKey=CCOLHPSRQAWQTN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125577   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM125577 (US8772316, 60) Show SMILES CNc1nc2cc3OCOc3cc2cc1Cc1c2cc(OC)c(OC)cc2c(C)[nH]c1=O Show InChI InChI=1S/C24H23N3O5/c1-12-15-8-19(29-3)20(30-4)9-16(15)17(24(28)26-12)6-14-5-13-7-21-22(32-11-31-21)10-18(13)27-23(14)25-2/h5,7-10H,6,11H2,1-4H3,(H,25,27)(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	7.4	n/a
Allergan, Inc.; Exonhit Therapeutics SA US Patent					Assay Description The PDE assay is based on the homogenous time-resolved fluorescence resonance energy transfer (TR-FRET) technology (LANCE from Perkin Elmer). This co...				US Patent US8772316 (2014) BindingDB Entry DOI: 10.7270/Q2Q81BR8
					More data for this Ligand-Target Pair