BDBM126174 US8778957, 64

SMILES: O=C1Nc2ncccc2[C@@]11Cc2cc3ccc(CN4CCNCC4c4ccccc4)nc3cc2C1

InChI Key: InChIKey=VIQHXAGIJWNLOX-BTMGADRYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 126174   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide (CGRP alpha) (Homo sapiens (Human))	BDBM126174 (US8778957, 64) Show SMILES O=C1Nc2ncccc2[C@@]11Cc2cc3ccc(CN4CCNCC4c4ccccc4)nc3cc2C1 |r| Show InChI InChI=1S/C29H27N5O/c35-28-29(24-7-4-10-31-27(24)33-28)15-21-13-20-8-9-23(32-25(20)14-22(21)16-29)18-34-12-11-30-17-26(34)19-5-2-1-3-6-19/h1-10,13-14,26,30H,11-12,15-18H2,(H,31,33,35)/t26?,29-/m0/s1	Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.60	-11.2	n/a	n/a	n/a	n/a	n/a	7.4	25
Merck Sharp & Dohme Corp. US Patent					Assay Description Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...				US Patent US8778957 (2014) BindingDB Entry DOI: 10.7270/Q29022G8
					More data for this Ligand-Target Pair