BDBM126175 US8778957, 95
SMILES: CC1(Cc2ccccc2)N(Cc2ccc3cc4C[C@@]5(Cc4cc3n2)C(=O)Nc2ncccc52)CC2(CCCC2)NC1=O
InChI Key: InChIKey=UACVZJDYLGCPBW-XZEQTHJSSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Calcitonin gene-related peptide (CGRP alpha) (Homo sapiens (Human)) | BDBM126175 (US8778957, 95) | Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 17 | -10.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl... | US Patent US8778957 (2014) BindingDB Entry DOI: 10.7270/Q29022G8 | |||||||||||
More data for this Ligand-Target Pair |