BDBM126181 US8778957, 27

SMILES: CN1CC2CN(Cc3ccc4cc5CC6(Cc5cc4n3)C(=O)Nc3ncccc63)CC2C1

InChI Key: InChIKey=ZWDXVXXJCSEOJC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 126181   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide (CGRP alpha) (Homo sapiens (Human))	BDBM126181 (US8778957, 27) Show SMILES CN1CC2CN(Cc3ccc4cc5CC6(Cc5cc4n3)C(=O)Nc3ncccc63)CC2C1 Show InChI InChI=1S/C26H27N5O/c1-30-11-19-13-31(14-20(19)12-30)15-21-5-4-16-7-17-9-26(10-18(17)8-23(16)28-21)22-3-2-6-27-24(22)29-25(26)32/h2-8,19-20H,9-15H2,1H3,(H,27,29,32)	Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	150	-9.30	n/a	n/a	n/a	n/a	n/a	7.4	25
Merck Sharp & Dohme Corp. US Patent					Assay Description Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...				US Patent US8778957 (2014) BindingDB Entry DOI: 10.7270/Q29022G8
					More data for this Ligand-Target Pair