BDBM126188 US8778957, 184

SMILES: CC(C)[C@H]1CN(C)CCN1Cc1ccc2cc3CC4(Cc3cc2n1)C(C)C(=O)NC4=O

InChI Key: InChIKey=JFQVNOLOYOZRPO-PMBLGMBLSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 126188   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide (CGRP alpha) (Homo sapiens (Human))	BDBM126188 (US8778957, 184) Show SMILES CC(C)[C@H]1CN(C)CCN1Cc1ccc2cc3CC4(Cc3cc2n1)C(C)C(=O)NC4=O |r| Show InChI InChI=1S/C25H32N4O2/c1-15(2)22-14-28(4)7-8-29(22)13-20-6-5-17-9-18-11-25(12-19(18)10-21(17)26-20)16(3)23(30)27-24(25)31/h5-6,9-10,15-16,22H,7-8,11-14H2,1-4H3,(H,27,30,31)/t16?,22-,25?/m1/s1	Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.70E+3	-7.87	n/a	n/a	n/a	n/a	n/a	7.4	25
Merck Sharp & Dohme Corp. US Patent					Assay Description Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...				US Patent US8778957 (2014) BindingDB Entry DOI: 10.7270/Q29022G8
					More data for this Ligand-Target Pair