BDBM126190 US8778957, 45

SMILES: O=C1Nc2ncccc2C11Cc2cc3ccc(CN4CCc5c(C4)[nH]c4ccccc54)nc3cc2C1

InChI Key: InChIKey=JALAUDYZJYMINL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 126190   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide (CGRP alpha) (Homo sapiens (Human))	BDBM126190 (US8778957, 45) Show SMILES O=C1Nc2ncccc2C11Cc2cc3ccc(CN4CCc5c(C4)[nH]c4ccccc54)nc3cc2C1 Show InChI InChI=1S/C30H25N5O/c36-29-30(24-5-3-10-31-28(24)34-29)14-19-12-18-7-8-21(32-26(18)13-20(19)15-30)16-35-11-9-23-22-4-1-2-6-25(22)33-27(23)17-35/h1-8,10,12-13,33H,9,11,14-17H2,(H,31,34,36)	Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	180	-9.19	n/a	n/a	n/a	n/a	n/a	7.4	25
Merck Sharp & Dohme Corp. US Patent					Assay Description Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...				US Patent US8778957 (2014) BindingDB Entry DOI: 10.7270/Q29022G8
					More data for this Ligand-Target Pair