BDBM126559 US8772283, 3

SMILES: NC1(CCC1)c1ccc(cc1)-c1nc2-c3c(F)cccc3OCn2c1-c1ccccc1

InChI Key: InChIKey=WWHZFUWEJSHFEY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 126559   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human))	BDBM126559 (US8772283, 3) Show SMILES NC1(CCC1)c1ccc(cc1)-c1nc2-c3c(F)cccc3OCn2c1-c1ccccc1 Show InChI InChI=1S/C26H22FN3O/c27-20-8-4-9-21-22(20)25-29-23(17-10-12-19(13-11-17)26(28)14-5-15-26)24(30(25)16-31-21)18-6-2-1-3-7-18/h1-4,6-13H,5,14-16,28H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.5	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...				US Patent US8772283 (2014) BindingDB Entry DOI: 10.7270/Q21J98F0
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM126559 (US8772283, 3) Show SMILES NC1(CCC1)c1ccc(cc1)-c1nc2-c3c(F)cccc3OCn2c1-c1ccccc1 Show InChI InChI=1S/C26H22FN3O/c27-20-8-4-9-21-22(20)25-29-23(17-10-12-19(13-11-17)26(28)14-5-15-26)24(30(25)16-31-21)18-6-2-1-3-7-18/h1-4,6-13H,5,14-16,28H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	7.5	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...				US Patent US8772283 (2014) BindingDB Entry DOI: 10.7270/Q21J98F0
					More data for this Ligand-Target Pair