BDBM126562 US8772283, 6

SMILES:

InChI Key: InChIKey=AGBCODKMADFEEP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 126562   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human))	BDBM126562 (US8772283, 6) Show SMILES Show InChI InChI=1S/C25H22FN3O2S/c1-24(30)12-25(27,13-24)17-7-5-15(6-8-17)21-22(16-9-10-32-11-16)29-14-31-19-4-2-3-18(26)20(19)23(29)28-21/h2-11,30H,12-14,27H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.910	n/a	n/a	n/a	n/a	7.5	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...				US Patent US8772283 (2014) BindingDB Entry DOI: 10.7270/Q21J98F0
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM126562 (US8772283, 6) Show SMILES Show InChI InChI=1S/C25H22FN3O2S/c1-24(30)12-25(27,13-24)17-7-5-15(6-8-17)21-22(16-9-10-32-11-16)29-14-31-19-4-2-3-18(26)20(19)23(29)28-21/h2-11,30H,12-14,27H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.80	n/a	n/a	n/a	n/a	7.5	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...				US Patent US8772283 (2014) BindingDB Entry DOI: 10.7270/Q21J98F0
					More data for this Ligand-Target Pair