null

SMILES: NC1(CC(O)(C1)C1CC1)c1ccc(cc1)-c1nc2-c3ccccc3OCn2c1-c1ccccc1

InChI Key: InChIKey=WXAOGAQSUJSHFI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 126567   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human))	BDBM126567 (US8772283, 11) Show SMILES NC1(CC(O)(C1)C1CC1)c1ccc(cc1)-c1nc2-c3ccccc3OCn2c1-c1ccccc1 |(7.56,3.47,;6.23,4.24,;5.14,5.33,;6.31,6.43,;6.36,7.97,;7.32,5.33,;4.9,7.07,;3.42,6.67,;4.51,8.55,;4.89,3.47,;3.56,4.24,;2.23,3.47,;2.23,1.93,;3.56,1.16,;4.89,1.93,;.93,1.09,;-.5,1.64,;-1.47,.45,;-3.01,.45,;-3.78,1.78,;-5.32,1.78,;-6.09,.45,;-5.32,-.89,;-3.78,-.89,;-3.01,-2.22,;-1.47,-2.22,;-.7,-.89,;.85,-.45,;2.06,-1.41,;1.66,-2.89,;2.75,-3.98,;4.23,-3.58,;4.63,-2.1,;3.54,-1.01,)| Show InChI InChI=1S/C29H27N3O2/c30-28(16-29(33,17-28)22-14-15-22)21-12-10-19(11-13-21)25-26(20-6-2-1-3-7-20)32-18-34-24-9-5-4-8-23(24)27(32)31-25/h1-13,22,33H,14-18,30H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...				US Patent US8772283 (2014) BindingDB Entry DOI: 10.7270/Q21J98F0
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM126567 (US8772283, 11) Show SMILES NC1(CC(O)(C1)C1CC1)c1ccc(cc1)-c1nc2-c3ccccc3OCn2c1-c1ccccc1 |(7.56,3.47,;6.23,4.24,;5.14,5.33,;6.31,6.43,;6.36,7.97,;7.32,5.33,;4.9,7.07,;3.42,6.67,;4.51,8.55,;4.89,3.47,;3.56,4.24,;2.23,3.47,;2.23,1.93,;3.56,1.16,;4.89,1.93,;.93,1.09,;-.5,1.64,;-1.47,.45,;-3.01,.45,;-3.78,1.78,;-5.32,1.78,;-6.09,.45,;-5.32,-.89,;-3.78,-.89,;-3.01,-2.22,;-1.47,-2.22,;-.7,-.89,;.85,-.45,;2.06,-1.41,;1.66,-2.89,;2.75,-3.98,;4.23,-3.58,;4.63,-2.1,;3.54,-1.01,)| Show InChI InChI=1S/C29H27N3O2/c30-28(16-29(33,17-28)22-14-15-22)21-12-10-19(11-13-21)25-26(20-6-2-1-3-7-20)32-18-34-24-9-5-4-8-23(24)27(32)31-25/h1-13,22,33H,14-18,30H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.90	n/a	n/a	n/a	n/a	7.5	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...				US Patent US8772283 (2014) BindingDB Entry DOI: 10.7270/Q21J98F0
					More data for this Ligand-Target Pair