BDBM126605 US8772283, 49

SMILES:

InChI Key: InChIKey=YTWTVQHWLVSHFR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 126605   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human))	BDBM126605 (US8772283, 49) Show SMILES Show InChI InChI=1S/C30H27N5O2/c1-29(36)16-30(31,17-29)23-10-7-19(8-11-23)26-27(20-5-3-2-4-6-20)35-18-37-25-12-9-21(22-14-32-33-15-22)13-24(25)28(35)34-26/h2-15,36H,16-18,31H2,1H3,(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.420	n/a	n/a	n/a	n/a	7.5	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...				US Patent US8772283 (2014) BindingDB Entry DOI: 10.7270/Q21J98F0
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM126605 (US8772283, 49) Show SMILES Show InChI InChI=1S/C30H27N5O2/c1-29(36)16-30(31,17-29)23-10-7-19(8-11-23)26-27(20-5-3-2-4-6-20)35-18-37-25-12-9-21(22-14-32-33-15-22)13-24(25)28(35)34-26/h2-15,36H,16-18,31H2,1H3,(H,32,33)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	7.5	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...				US Patent US8772283 (2014) BindingDB Entry DOI: 10.7270/Q21J98F0
					More data for this Ligand-Target Pair