null

SMILES:

InChI Key: InChIKey=YQYPEKJWQWODNB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 126614   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human))	BDBM126614 (US8772283, 58) Show SMILES Show InChI InChI=1S/C30H30N4O4/c1-29(37)16-30(31,17-29)22-10-7-19(8-11-22)25-26(20-5-3-2-4-6-20)34-18-38-24-15-21(28(36)32-13-14-35)9-12-23(24)27(34)33-25/h2-12,15,35,37H,13-14,16-18,31H2,1H3,(H,32,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	7.5	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...				US Patent US8772283 (2014) BindingDB Entry DOI: 10.7270/Q21J98F0
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM126614 (US8772283, 58) Show SMILES Show InChI InChI=1S/C30H30N4O4/c1-29(37)16-30(31,17-29)22-10-7-19(8-11-22)25-26(20-5-3-2-4-6-20)34-18-38-24-15-21(28(36)32-13-14-35)9-12-23(24)27(34)33-25/h2-12,15,35,37H,13-14,16-18,31H2,1H3,(H,32,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	7.5	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...				US Patent US8772283 (2014) BindingDB Entry DOI: 10.7270/Q21J98F0
					More data for this Ligand-Target Pair