BDBM126742 US8785489, 4-[({[1-methyl-5-(2-pyrimidin-2-yl-1H-indol-5-yl)-1H-pyrazol-3-yl]carbonyl}amino)methyl]benzoic acid
SMILES: Cn1nc(cc1-c1ccc2[nH]c(cc2c1)-c1ncccn1)C(=O)NCc1ccc(cc1)C(O)=O
InChI Key: InChIKey=LQGGGMNYWAAXAT-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Collagenase 3 (Mus musculus (Mouse)) | BDBM126742 (US8785489, 4-[({[1-methyl-5-(2-pyrimidin-2-yl-1H-i...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.) can detect the activity of several MMPs including MMP-1, 2, 3, 7, 8, 9, 13, and 14. This kit us... | US Patent US8785489 (2014) BindingDB Entry DOI: 10.7270/Q24B300F | |||||||||||
More data for this Ligand-Target Pair |