BDBM126743 US8785489, N-(1,4-dioxan-2-ylmethyl)-5-methyl-4-[2-(3-methyl-1,2,4-oxadiazol-5-yl)-1H-indol-5-yl]-1H-imidazole-2-carboxamide

SMILES: Cc1noc(n1)-c1cc2cc(ccc2[nH]1)-c1nc([nH]c1C)C(=O)NCC1COCCO1

InChI Key: InChIKey=IEJLDQDLJZGGHB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 126743   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Mus musculus (Mouse))	BDBM126743 (US8785489, N-(1,4-dioxan-2-ylmethyl)-5-methyl-4-[2...) Show SMILES Cc1noc(n1)-c1cc2cc(ccc2[nH]1)-c1nc([nH]c1C)C(=O)NCC1COCCO1 Show InChI InChI=1S/C21H22N6O4/c1-11-18(26-19(23-11)20(28)22-9-15-10-29-5-6-30-15)13-3-4-16-14(7-13)8-17(25-16)21-24-12(2)27-31-21/h3-4,7-8,15,25H,5-6,9-10H2,1-2H3,(H,22,28)(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.) can detect the activity of several MMPs including MMP-1, 2, 3, 7, 8, 9, 13, and 14. This kit us...				US Patent US8785489 (2014) BindingDB Entry DOI: 10.7270/Q24B300F
					More data for this Ligand-Target Pair