BDBM126753 US8785489, 4-[({[1-methyl-5-(2-pyridin-3-yl-1H-indol-5-yl)-1H-pyrazol-3-yl]carbonyl}amino)methyl]benzoic acid

SMILES: Cn1nc(cc1-c1ccc2[nH]c(cc2c1)-c1cccnc1)C(=O)NCc1ccc(cc1)C(O)=O

InChI Key: InChIKey=IFTRAWSZKLIIEY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 126753   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metallopeptidase 13 (MMP13) (Mus musculus (Mouse))	BDBM126753 (US8785489, 4-[({[1-methyl-5-(2-pyridin-3-yl-1H-ind...) Show SMILES Cn1nc(cc1-c1ccc2[nH]c(cc2c1)-c1cccnc1)C(=O)NCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C26H21N5O3/c1-31-24(13-23(30-31)25(32)28-14-16-4-6-17(7-5-16)26(33)34)18-8-9-21-20(11-18)12-22(29-21)19-3-2-10-27-15-19/h2-13,15,29H,14H2,1H3,(H,28,32)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.) can detect the activity of several MMPs including MMP-1, 2, 3, 7, 8, 9, 13, and 14. This kit us...				US Patent US8785489 (2014) BindingDB Entry DOI: 10.7270/Q24B300F
					More data for this Ligand-Target Pair