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SMILES: CCOC(=O)c1[nH]c2ccc(cc2c1F)-c1nc([nH]c1C)C(=O)NCc1ccncc1

InChI Key: InChIKey=GTIUUFDCOLSPJI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 126767   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Collagenase 3


(Mus musculus (Mouse))		BDBM126767
PNG
(US8785489, ethyl 3-fluoro-5-{5-methyl-2-[(pyridin-...)
Show SMILES CCOC(=O)c1[nH]c2ccc(cc2c1F)-c1nc([nH]c1C)C(=O)NCc1ccncc1
Show InChI InChI=1S/C22H20FN5O3/c1-3-31-22(30)19-17(23)15-10-14(4-5-16(15)27-19)18-12(2)26-20(28-18)21(29)25-11-13-6-8-24-9-7-13/h4-10,27H,3,11H2,1-2H3,(H,25,29)(H,26,28)
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MMDB

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Similars
US Patent
n/an/a 7n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.) can detect the activity of several MMPs including MMP-1, 2, 3, 7, 8, 9, 13, and 14. This kit us...

US Patent US8785489 (2014)


BindingDB Entry DOI: 10.7270/Q24B300F
More data for this
Ligand-Target Pair