BDBM126768 US8785489, ethyl 5-{5-methyl-2-[(pyridin-4-ylmethyl)carbamoyl]-1H-imidazol-4-yl}-1H-pyrrolo[2,3-c]pyridine-2-carboxylate

SMILES: CCOC(=O)c1cc2cc(ncc2[nH]1)-c1nc([nH]c1C)C(=O)NCc1ccncc1

InChI Key: InChIKey=FNZCCNYXWBUTMG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 126768   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Mus musculus (Mouse))	BDBM126768 (US8785489, ethyl 5-{5-methyl-2-[(pyridin-4-ylmethy...) Show SMILES CCOC(=O)c1cc2cc(ncc2[nH]1)-c1nc([nH]c1C)C(=O)NCc1ccncc1 Show InChI InChI=1S/C21H20N6O3/c1-3-30-21(29)16-9-14-8-15(23-11-17(14)26-16)18-12(2)25-19(27-18)20(28)24-10-13-4-6-22-7-5-13/h4-9,11,26H,3,10H2,1-2H3,(H,24,28)(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The EnzoLyte 520 Generic MMP Assay Kit (AnaSpec Inc.) can detect the activity of several MMPs including MMP-1, 2, 3, 7, 8, 9, 13, and 14. This kit us...				US Patent US8785489 (2014) BindingDB Entry DOI: 10.7270/Q24B300F
					More data for this Ligand-Target Pair