BDBM127218 US8791272, 7.14

SMILES: Cc1nn(Cc2ccc(NC(=O)c3ccc(cc3C)C(F)(F)F)cc2Cl)c(C)c1CC(O)=O

InChI Key: InChIKey=KPOVFNNOIHPOFG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 127218   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM127218 (US8791272, 7.14) Show SMILES Cc1nn(Cc2ccc(NC(=O)c3ccc(cc3C)C(F)(F)F)cc2Cl)c(C)c1CC(O)=O Show InChI InChI=1S/C23H21ClF3N3O3/c1-12-8-16(23(25,26)27)5-7-18(12)22(33)28-17-6-4-15(20(24)9-17)11-30-14(3)19(10-21(31)32)13(2)29-30/h4-9H,10-11H2,1-3H3,(H,28,33)(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.60	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair