BDBM127245 US8791272, 9.13

SMILES: CCc1nn(Cc2ccc(cc2)C(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)c(CC)c1CC(O)=O

InChI Key: InChIKey=VZCFDSXQIYVLNX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 127245   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM127245 (US8791272, 9.13) Show SMILES CCc1nn(Cc2ccc(cc2)C(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)c(CC)c1CC(O)=O Show InChI InChI=1S/C24H23ClF3N3O3/c1-3-20-17(12-22(32)33)21(4-2)31(30-20)13-14-5-7-15(8-6-14)23(34)29-16-9-10-19(25)18(11-16)24(26,27)28/h5-11H,3-4,12-13H2,1-2H3,(H,29,34)(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.900	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair