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SMILES: CCc1nn(C(C)c2ccc(NC(=O)c3ccc(cc3)C(F)(F)F)cc2)c(CC)c1CC(O)=O

InChI Key: InChIKey=USJJSTKMNPRWIB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 127296   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM127296
PNG
(US8791272, 17.1)
Show SMILES CCc1nn(C(C)c2ccc(NC(=O)c3ccc(cc3)C(F)(F)F)cc2)c(CC)c1CC(O)=O
Show InChI InChI=1S/C25H26F3N3O3/c1-4-21-20(14-23(32)33)22(5-2)31(30-21)15(3)16-8-12-19(13-9-16)29-24(34)17-6-10-18(11-7-17)25(26,27)28/h6-13,15H,4-5,14H2,1-3H3,(H,29,34)(H,32,33)
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Similars
US Patent
 0.100n/an/an/an/an/an/a7.4n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...

US Patent US8791272 (2014)


BindingDB Entry DOI: 10.7270/Q2GH9GNV
More data for this
Ligand-Target Pair