null
SMILES: CCC(Nc1cc(C)cc(CN2CC(C2)C(O)=O)c1)c1ccc(Cl)c(C)c1
InChI Key: InChIKey=XZKTZIQYJMCHLM-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human)) | BDBM127511 (US8791100, 9) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | 37 |
Novartis AG US Patent | Assay Description The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5... | US Patent US8791100 (2014) BindingDB Entry DOI: 10.7270/Q2ZK5FCC | |||||||||||
More data for this Ligand-Target Pair |