BDBM128250 US8796296, 14::US8796296, 5

SMILES: CNc1nc(Nc2cc3oc(=O)n(C)c3cc2Cl)ncc1C(F)(F)F

InChI Key: InChIKey=XAHLCECLVUVWOW-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 128250   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM128250 (US8796296, 14 | US8796296, 5) Show SMILES CNc1nc(Nc2cc3oc(=O)n(C)c3cc2Cl)ncc1C(F)(F)F Show InChI InChI=1S/C14H11ClF3N5O2/c1-19-11-6(14(16,17)18)5-20-12(22-11)21-8-4-10-9(3-7(8)15)23(2)13(24)25-10/h3-5H,1-2H3,(H2,19,20,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description his assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 38...				US Patent US8796296 (2014) BindingDB Entry DOI: 10.7270/Q28W3C0R
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM128250 (US8796296, 14 | US8796296, 5) Show SMILES CNc1nc(Nc2cc3oc(=O)n(C)c3cc2Cl)ncc1C(F)(F)F Show InChI InChI=1S/C14H11ClF3N5O2/c1-19-11-6(14(16,17)18)5-20-12(22-11)21-8-4-10-9(3-7(8)15)23(2)13(24)25-10/h3-5H,1-2H3,(H2,19,20,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description his assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 38...				US Patent US8796296 (2014) BindingDB Entry DOI: 10.7270/Q28W3C0R
					More data for this Ligand-Target Pair