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SMILES: CNc1nc(Nc2cc3nc(C)oc3cc2Cl)ncc1C(F)(F)F

InChI Key: InChIKey=UJGKVPASFSOSHW-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 128251   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Leucine-rich repeat serine/threonine-protein kinase 2


(Homo sapiens (Human))		BDBM128251
PNG
(US8796296, 6)
Show SMILES CNc1nc(Nc2cc3nc(C)oc3cc2Cl)ncc1C(F)(F)F
Show InChI InChI=1S/C14H11ClF3N5O/c1-6-21-10-4-9(8(15)3-11(10)24-6)22-13-20-5-7(14(16,17)18)12(19-2)23-13/h3-5H,1-2H3,(H2,19,20,22,23)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
 5n/an/an/an/an/an/an/an/a



Genentech, Inc.

US Patent


Assay Description
his assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 38...

US Patent US8796296 (2014)


BindingDB Entry DOI: 10.7270/Q28W3C0R
More data for this
Ligand-Target Pair