BDBM128252 US8796296, 7

SMILES: CNc1nc(Nc2cc3C(=O)N(C)Cc3cc2OC)ncc1C(F)(F)F

InChI Key: InChIKey=FZWHIGMFGDFLCO-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 128252   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM128252 (US8796296, 7) Show SMILES CNc1nc(Nc2cc3C(=O)N(C)Cc3cc2OC)ncc1C(F)(F)F Show InChI InChI=1S/C16H16F3N5O2/c1-20-13-10(16(17,18)19)6-21-15(23-13)22-11-5-9-8(4-12(11)26-3)7-24(2)14(9)25/h4-6H,7H2,1-3H3,(H2,20,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description his assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 38...				US Patent US8796296 (2014) BindingDB Entry DOI: 10.7270/Q28W3C0R
					More data for this Ligand-Target Pair