BDBM128258 US8796296, 13

SMILES: CNc1nc(Nc2cc3oc(=O)[nH]c3cc2Cl)ncc1Cl

InChI Key: InChIKey=PDELIAMVWVPYOD-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 128258   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM128258 (US8796296, 13) Show SMILES CNc1nc(Nc2cc3oc(=O)[nH]c3cc2Cl)ncc1Cl Show InChI InChI=1S/C12H9Cl2N5O2/c1-15-10-6(14)4-16-11(19-10)17-7-3-9-8(2-5(7)13)18-12(20)21-9/h2-4H,1H3,(H,18,20)(H2,15,16,17,19)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description his assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 38...				US Patent US8796296 (2014) BindingDB Entry DOI: 10.7270/Q28W3C0R
					More data for this Ligand-Target Pair