BDBM128358 US8802864, 7
SMILES: Cn1nc(C[C@@H]2CCN(C2)C(=O)C2CC2)n(-c2ccc(cc2)-c2ccc3occc3c2)c1=O
InChI Key: InChIKey=SEQBBDLZUXJXRX-KRWDZBQOSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fatty acid synthase (Homo sapiens (Human)) | BDBM128358 (US8802864, 7) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | 7.0 | n/a |
GlaxoSmithKline LLC US Patent | Assay Description Assay #1:Inhibition of FAS activity can be measured based on the detection of residual NADPH substrate after the FAS assay is quenched. This assay is... | US Patent US8802864 (2014) BindingDB Entry DOI: 10.7270/Q2N58K26 | |||||||||||
More data for this Ligand-Target Pair |