null
SMILES: O=C(C1CC1)N1CC[C@@H](Cc2n[nH]c(=O)n2-c2ccc(cc2)-c2ccc3OCOc3c2)C1
InChI Key: InChIKey=IJSKDJVOKJTYAV-HNNXBMFYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fatty acid synthase (Homo sapiens (Human)) | BDBM128361 (US8802864, 38) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 158 | n/a | n/a | n/a | n/a | 7.0 | n/a |
GlaxoSmithKline LLC US Patent | Assay Description Assay #1:Inhibition of FAS activity can be measured based on the detection of residual NADPH substrate after the FAS assay is quenched. This assay is... | US Patent US8802864 (2014) BindingDB Entry DOI: 10.7270/Q2N58K26 | |||||||||||
More data for this Ligand-Target Pair |