BDBM128369 US8802861, 6

SMILES: CC(=O)Nc1nc(C)c(s1)-c1csc(NCC=C)n1

InChI Key: InChIKey=IJWWVKWSFPHCMW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 128369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM128369 (US8802861, 6) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1csc(NCC=C)n1 Show InChI InChI=1S/C12H14N4OS2/c1-4-5-13-11-16-9(6-18-11)10-7(2)14-12(19-10)15-8(3)17/h4,6H,1,5H2,2-3H3,(H,13,16)(H,14,15,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	202	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono SA US Patent					Assay Description The efficacy of compounds of the invention in inhibiting the PI3K induced-lipid phosphorylation may be tested in the following binding assay.The assa...				US Patent US8802861 (2014) BindingDB Entry DOI: 10.7270/Q2HD7TCX
					More data for this Ligand-Target Pair