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SMILES: Cc1cc2c(NC(=O)N[C@H]3CC[C@@H](C3)c3cccc(F)c3)c(F)ccc2cn1

InChI Key: InChIKey=PAFRMBKESKKSIA-YJBOKZPZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 128905   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM128905
PNG
(US8802711, 74)
Show SMILES Cc1cc2c(NC(=O)N[C@H]3CC[C@@H](C3)c3cccc(F)c3)c(F)ccc2cn1
Show InChI InChI=1S/C22H21F2N3O/c1-13-9-19-16(12-25-13)6-8-20(24)21(19)27-22(28)26-18-7-5-15(11-18)14-3-2-4-17(23)10-14/h2-4,6,8-10,12,15,18H,5,7,11H2,1H3,(H2,26,27,28)/t15-,18-/m0/s1
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Similars
US Patent
n/an/a 3.5n/an/an/an/an/an/a



AbbVie Inc.

US Patent


Assay Description
The functional activity of compounds at the TRPV1 receptor was determined by measurement of intracellular Ca2+ levels ([Ca2+]i) using the Fluorescenc...

US Patent US8802711 (2014)


BindingDB Entry DOI: 10.7270/Q2QZ28NC
More data for this
Ligand-Target Pair