BDBM129028 US8802674, 53

SMILES: CNc1nc(Nc2ccc(cc2OC)C(=O)NC(C)C)ncc1Cl

InChI Key: InChIKey=TXCLIQGRJADRRX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 129028   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM129028 (US8802674, 53) Show SMILES CNc1nc(Nc2ccc(cc2OC)C(=O)NC(C)C)ncc1Cl Show InChI InChI=1S/C16H20ClN5O2/c1-9(2)20-15(23)10-5-6-12(13(7-10)24-4)21-16-19-8-11(17)14(18-3)22-16/h5-9H,1-4H3,(H,20,23)(H2,18,19,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. ...				US Patent US8802674 (2014) BindingDB Entry DOI: 10.7270/Q2GF0S6N
					More data for this Ligand-Target Pair