BDBM129042 US8802674, 76

SMILES: CNc1nc(Nc2ccc(cc2OC)C(=O)N2CCC(CC2)OC)ncc1Br

InChI Key: InChIKey=JCWOSAJJQWUEQS-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 129042   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM129042 (US8802674, 76) Show SMILES CNc1nc(Nc2ccc(cc2OC)C(=O)N2CCC(CC2)OC)ncc1Br Show InChI InChI=1S/C19H24BrN5O3/c1-21-17-14(20)11-22-19(24-17)23-15-5-4-12(10-16(15)28-3)18(26)25-8-6-13(27-2)7-9-25/h4-5,10-11,13H,6-9H2,1-3H3,(H2,21,22,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. ...				US Patent US8802674 (2014) BindingDB Entry DOI: 10.7270/Q2GF0S6N
					More data for this Ligand-Target Pair