BDBM129049 US8802674, 83

SMILES: CCN1CCN(CC1)C(=O)c1ccc(Nc2ncc(Br)c(OC)n2)c(OC)c1

InChI Key: InChIKey=MCHRGWRYQYWQBX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 129049   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM129049 (US8802674, 83) Show SMILES CCN1CCN(CC1)C(=O)c1ccc(Nc2ncc(Br)c(OC)n2)c(OC)c1 Show InChI InChI=1S/C19H24BrN5O3/c1-4-24-7-9-25(10-8-24)18(26)13-5-6-15(16(11-13)27-2)22-19-21-12-14(20)17(23-19)28-3/h5-6,11-12H,4,7-10H2,1-3H3,(H,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. ...				US Patent US8802674 (2014) BindingDB Entry DOI: 10.7270/Q2GF0S6N
					More data for this Ligand-Target Pair