BDBM129457 US8802673, 99

SMILES: Fc1cc(ccc1Nc1ccc(Cl)cn1)C1CNCCO1

InChI Key: InChIKey=ZUJGDENZVATUCK-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 129457   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trace amine-associated receptor 1 (TAAR1) (Mus musculus (Mouse))	BDBM129457 (US8802673, 99) Show SMILES Fc1cc(ccc1Nc1ccc(Cl)cn1)C1CNCCO1 Show InChI InChI=1S/C15H15ClFN3O/c16-11-2-4-15(19-8-11)20-13-3-1-10(7-12(13)17)14-9-18-5-6-21-14/h1-4,7-8,14,18H,5-6,9H2,(H,19,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.800	-12.9	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1) (Rattus norvegicus (Rat))	BDBM129457 (US8802673, 99) Show SMILES Fc1cc(ccc1Nc1ccc(Cl)cn1)C1CNCCO1 Show InChI InChI=1S/C15H15ClFN3O/c16-11-2-4-15(19-8-11)20-13-3-1-10(7-12(13)17)14-9-18-5-6-21-14/h1-4,7-8,14,18H,5-6,9H2,(H,19,20)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	18.5	-11.0	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...				US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G
					More data for this Ligand-Target Pair