null

SMILES: COc1cc(OC)c(F)c(c1F)-c1ccc(C(=O)Nc2ccc(CN3CCNCC3)cn2)c2nccnc12

InChI Key: InChIKey=XNOQKRCZJXLTHH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 130076   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM130076 (US8815901, 124) Show SMILES COc1cc(OC)c(F)c(c1F)-c1ccc(C(=O)Nc2ccc(CN3CCNCC3)cn2)c2nccnc12 |(10.39,-2.67,;8.85,-2.67,;8.08,-1.33,;8.85,,;8.08,1.33,;8.85,2.67,;8.08,4,;6.54,1.33,;5.78,2.67,;5.78,,;6.54,-1.33,;5.78,-2.67,;4.23,,;3.47,1.33,;1.93,1.33,;1.15,,;-.38,,;-1.15,1.33,;-1.15,-1.33,;-2.69,-1.33,;-3.47,,;-5,,;-5.78,-1.33,;-7.31,-1.33,;-8.08,,;-7.31,1.33,;-8.08,2.67,;-9.63,2.67,;-10.39,1.33,;-9.63,,;-5,-2.67,;-3.47,-2.67,;1.93,-1.33,;1.15,-2.67,;1.93,-4,;3.47,-4,;4.23,-2.67,;3.47,-1.33,)| Show InChI InChI=1S/C27H26F2N6O3/c1-37-19-13-20(38-2)24(29)22(23(19)28)17-4-5-18(26-25(17)31-7-8-32-26)27(36)34-21-6-3-16(14-33-21)15-35-11-9-30-10-12-35/h3-8,13-14,30H,9-12,15H2,1-2H3,(H,33,34,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description The assay has been run at room temperature on a liquid handling robot. To the assay plates containing 50 mL compound or control solutions, 4.5 uL of ...				US Patent US8815901 (2014) BindingDB Entry DOI: 10.7270/Q2XG9PT8
					More data for this Ligand-Target Pair