null

SMILES: COc1cc(OC)c(Cl)c(c1F)-c1ccc(C(=O)Nc2ncc(CN(C)C)[nH]2)c2ncccc12

InChI Key: InChIKey=AILPSTKPMGDNML-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 130084   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM130084 (US8815901, 177) Show SMILES COc1cc(OC)c(Cl)c(c1F)-c1ccc(C(=O)Nc2ncc(CN(C)C)[nH]2)c2ncccc12 |(7.33,3.93,;8.1,2.59,;7.33,1.26,;8.1,-.08,;7.33,-1.41,;8.1,-2.74,;9.64,-2.74,;5.79,-1.41,;5.02,-2.74,;5.02,-.08,;5.79,1.26,;5.02,2.59,;3.48,-.08,;2.71,1.26,;1.17,1.26,;.4,-.08,;-1.14,-.08,;-1.91,1.26,;-1.91,-1.41,;-3.44,-1.41,;-4.34,-.16,;-5.81,-.64,;-5.81,-2.18,;-7.14,-2.95,;-8.48,-2.18,;-9.81,-2.95,;-8.48,-.64,;-4.34,-2.65,;1.17,-1.41,;.4,-2.74,;1.17,-4.08,;2.71,-4.08,;3.48,-2.74,;2.71,-1.41,)| Show InChI InChI=1S/C24H23ClFN5O3/c1-31(2)12-13-11-28-24(29-13)30-23(32)16-8-7-14(15-6-5-9-27-22(15)16)19-20(25)17(33-3)10-18(34-4)21(19)26/h5-11H,12H2,1-4H3,(H2,28,29,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description The assay has been run at room temperature on a liquid handling robot. To the assay plates containing 50 mL compound or control solutions, 4.5 uL of ...				US Patent US8815901 (2014) BindingDB Entry DOI: 10.7270/Q2XG9PT8
					More data for this Ligand-Target Pair