null
SMILES: OC(=O)C[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)NC(=O)c1n[nH]c(=O)o1
InChI Key: InChIKey=PHCKQOWLJHBMLK-OAHLLOKOSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human)) | BDBM130360 (US8822534, Example 5-46 | US8993631, 5-9) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat... | US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human)) | BDBM130360 (US8822534, Example 5-46 | US8993631, 5-9) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat... | US Patent US8822534 (2014) BindingDB Entry DOI: 10.7270/Q2513WW2 | |||||||||||
More data for this Ligand-Target Pair |