BDBM130376 N-[2-Benzyl-4-(1H-1,2,3,4-tetrazol-5-yl)phenyl]-6-(cyclohexylmethyl)pyridine-2- carboxamide (2)

SMILES: O=C(Nc1ccc(cc1Cc1ccccc1)-c1nnn[nH]1)c1cccc(CC2CCCCC2)n1

InChI Key: InChIKey=DXIJKKFLXBIMCT-UHFFFAOYSA-N

Data: 3 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 130376   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein UL24 homolog (Human herpesvirus 8)	BDBM130376 (N-[2-Benzyl-4-(1H-1,2,3,4-tetrazol-5-yl)phenyl]-6-...) Show SMILES O=C(Nc1ccc(cc1Cc1ccccc1)-c1nnn[nH]1)c1cccc(CC2CCCCC2)n1 Show InChI InChI=1S/C27H28N6O/c34-27(25-13-7-12-23(28-25)17-20-10-5-2-6-11-20)29-24-15-14-21(26-30-32-33-31-26)18-22(24)16-19-8-3-1-4-9-19/h1,3-4,7-9,12-15,18,20H,2,5-6,10-11,16-17H2,(H,29,34)(H,30,31,32,33)	MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	8.0	n/a
University of California at San Francisco					Assay Description Compounds were prepared in 100% DMSO from 10 to 0.156 mM and/or from 5 to 0.078 mM. The P6 substrate concentrations were 5, 65, and 150 µM for KSHV, ...				Biochemistry 53: 4648-60 (2014) Article DOI: 10.1021/bi5003234 BindingDB Entry DOI: 10.7270/Q2WH2NQW
					More data for this Ligand-Target Pair
Epstein-Barr nuclear antigen 1 (Human herpesvirus 4)	BDBM130376 (N-[2-Benzyl-4-(1H-1,2,3,4-tetrazol-5-yl)phenyl]-6-...) Show SMILES O=C(Nc1ccc(cc1Cc1ccccc1)-c1nnn[nH]1)c1cccc(CC2CCCCC2)n1 Show InChI InChI=1S/C27H28N6O/c34-27(25-13-7-12-23(28-25)17-20-10-5-2-6-11-20)29-24-15-14-21(26-30-32-33-31-26)18-22(24)16-19-8-3-1-4-9-19/h1,3-4,7-9,12-15,18,20H,2,5-6,10-11,16-17H2,(H,29,34)(H,30,31,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	8.0	n/a
University of California at San Francisco					Assay Description Compounds were prepared in 100% DMSO from 10 to 0.156 mM and/or from 5 to 0.078 mM. The P6 substrate concentrations were 5, 65, and 150 µM for KSHV, ...				Biochemistry 53: 4648-60 (2014) Article DOI: 10.1021/bi5003234 BindingDB Entry DOI: 10.7270/Q2WH2NQW
					More data for this Ligand-Target Pair
Capsid scaffolding protein (Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)	BDBM130376 (N-[2-Benzyl-4-(1H-1,2,3,4-tetrazol-5-yl)phenyl]-6-...) Show SMILES O=C(Nc1ccc(cc1Cc1ccccc1)-c1nnn[nH]1)c1cccc(CC2CCCCC2)n1 Show InChI InChI=1S/C27H28N6O/c34-27(25-13-7-12-23(28-25)17-20-10-5-2-6-11-20)29-24-15-14-21(26-30-32-33-31-26)18-22(24)16-19-8-3-1-4-9-19/h1,3-4,7-9,12-15,18,20H,2,5-6,10-11,16-17H2,(H,29,34)(H,30,31,32,33)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	8.0	n/a
University of California at San Francisco					Assay Description Compounds were prepared in 100% DMSO from 10 to 0.156 mM and/or from 5 to 0.078 mM. The P6 substrate concentrations were 5, 65, and 150 µM for KSHV, ...				Biochemistry 53: 4648-60 (2014) Article DOI: 10.1021/bi5003234 BindingDB Entry DOI: 10.7270/Q2WH2NQW
					More data for this Ligand-Target Pair