BDBM130392 US8822510, 63
SMILES: OC(=O)C1CN(Cc2ccc(cc2)-c2noc(CCC3(CCCCC3)c3ccc(F)cc3)n2)C1
InChI Key: InChIKey=DMPAAYFQWGNDNK-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human)) | BDBM130392 (US8822510, 63) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.210 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1x 108 cells/pellet) were suspended in buffer containing 20 mM HEPES, pH... | US Patent US8822510 (2014) BindingDB Entry DOI: 10.7270/Q2H70DHC | |||||||||||
More data for this Ligand-Target Pair |