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BDBM130500 US8822479, 11

SMILES: Cc1ccccc1-n1ncc2c1nc(CC1CCCC1)[nH]c2=O

InChI Key: InChIKey=OABFLEIJFRAONO-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 130500   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 9A


(Homo sapiens (Human))
BDBM130500
PNG
(US8822479, 11)
Show SMILES Cc1ccccc1-n1ncc2c1nc(CC1CCCC1)[nH]c2=O
Show InChI InChI=1S/C18H20N4O/c1-12-6-2-5-9-15(12)22-17-14(11-19-22)18(23)21-16(20-17)10-13-7-3-4-8-13/h2,5-6,9,11,13H,3-4,7-8,10H2,1H3,(H,20,21,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

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DrugBank
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PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The test substances are dissolved in 100% DMSO and serially diluted to determine their in vitro effect on PDE 9A. Typically, serial dilutions from 20...


US Patent US8822479 (2014)

More data for this
Ligand-Target Pair