BDBM130512 US8822460, 8

SMILES: FC(F)(F)c1ccc2CCN(Cc2c1)C(=O)C12CCOC1CC(C2)NC1CCOCC1

InChI Key: InChIKey=HBUDXPHYMVPJQY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 130512   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM130512 (US8822460, 8) Show SMILES FC(F)(F)c1ccc2CCN(Cc2c1)C(=O)C12CCOC1CC(C2)NC1CCOCC1 Show InChI InChI=1S/C23H29F3N2O3/c24-23(25,26)17-2-1-15-3-7-28(14-16(15)11-17)21(29)22-6-10-31-20(22)12-19(13-22)27-18-4-8-30-9-5-18/h1-2,11,18-20,27H,3-10,12-14H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description THP-1 (cells were incubated with 0.5 nM 125I labeled MCP-1 (Perkin-Elmer Life Sciences, Inc. Boston, Mass.) in the presence of varying concentrations...				US Patent US8822460 (2014) BindingDB Entry DOI: 10.7270/Q208641R
					More data for this Ligand-Target Pair