BDBM130709 US8822448, 17

SMILES: Cc1cc2[nH]c(=O)c3cnn(C4CCOCC4)c3c2cc1C(=O)N1CCN(CC1)c1ccccn1

InChI Key: InChIKey=ZOAANKAHKASUSA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 130709   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 9 (PDE9) (Rattus norvegicus (Rat))	BDBM130709 (US8822448, 17) Show SMILES Cc1cc2[nH]c(=O)c3cnn(C4CCOCC4)c3c2cc1C(=O)N1CCN(CC1)c1ccccn1 Show InChI InChI=1S/C26H28N6O3/c1-17-14-22-20(24-21(25(33)29-22)16-28-32(24)18-5-12-35-13-6-18)15-19(17)26(34)31-10-8-30(9-11-31)23-4-2-3-7-27-23/h2-4,7,14-16,18H,5-6,8-13H2,1H3,(H,29,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.10	n/a	n/a	n/a	n/a	8.0	n/a
Astellas Pharma Inc. US Patent					Assay Description The PDE9-inhibiting activity was measured by the following method. That is, to a buffer solution containing tris(hydroxymethyl)aminomethane-hydrochlo...				US Patent US8822448 (2014) BindingDB Entry DOI: 10.7270/Q2BK1B1J
					More data for this Ligand-Target Pair