BDBM130710 US8822448, 22
SMILES: Cc1cc2[nH]c(=O)c3cnn(C4CCOCC4)c3c2cc1C(=O)N1CCC(CC1)Oc1ccccn1
InChI Key: InChIKey=NVJOREAYPULWFM-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphodiesterase 9 (PDE9) (Rattus norvegicus (Rat)) | BDBM130710 (US8822448, 22) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Astellas Pharma Inc. US Patent | Assay Description The PDE9-inhibiting activity was measured by the following method. That is, to a buffer solution containing tris(hydroxymethyl)aminomethane-hydrochlo... | US Patent US8822448 (2014) BindingDB Entry DOI: 10.7270/Q2BK1B1J | |||||||||||
More data for this Ligand-Target Pair |