BDBM13073 2000-07790::3-nitro-4-(2-oxopyrrolidin-1-yl)benzene-1-sulfonamide::LeadQuest Compound 7
SMILES: NS(=O)(=O)c1ccc(N2CCCC2=O)c(c1)[N+]([O-])=O
InChI Key: InChIKey=FPCPYSKJIRSWIG-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM13073 (2000-07790 | 3-nitro-4-(2-oxopyrrolidin-1-yl)benze...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 0.620 | n/a | n/a | n/a | n/a | 7.4 | 25 |
University of Marburg | Assay Description Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt... | J Med Chem 45: 3588-602 (2002) Article DOI: 10.1021/jm011112j BindingDB Entry DOI: 10.7270/Q2RJ4GQP | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |