BDBM130781 US8822448, 211
SMILES: C[C@H]1CN(CCN1CCC(F)(F)F)C(=O)c1cc2c3n(CC4CCC4)ncc3c(=O)[nH]c2cc1C
InChI Key: InChIKey=NEARNAAHNFNEBZ-INIZCTEOSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphodiesterase 9 (PDE9) (Rattus norvegicus (Rat)) | BDBM130781 (US8822448, 211) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Astellas Pharma Inc. US Patent | Assay Description The PDE9-inhibiting activity was measured by the following method. That is, to a buffer solution containing tris(hydroxymethyl)aminomethane-hydrochlo... | US Patent US8822448 (2014) BindingDB Entry DOI: 10.7270/Q2BK1B1J | |||||||||||
More data for this Ligand-Target Pair |